Gupta Brain Retraining Program
We don’t endorse any of the resources here, but only share what exists. Please do your own research. The information within our resources is from secondary sources, and is not intended to replace medical advice from a healthcare provider. Whilst we aim to provide as much information as we can for free, some of these resources will cost you money if you take them up. If there are scholarships or funding that we can find, we cite them in the resource.
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The Gupta Program is an online, self-directed brain retraining programme developed by Ashok Gupta, who personally recovered from ME/CFS. It’s based on the idea that chronic conditions like ME/CFS, fibromyalgia, and Long COVID are caused or sustained by a malfunctioning “fight, flight, or freeze” response in the brain — specifically involving the amygdala and insula.
The programme uses neuroplasticity techniques to retrain the brain’s stress response, calm the nervous system, and create new, healthier patterns for the body and mind. It blends cognitive, somatic, and mindfulness tools.
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The programme is structured around:
The “Amygdala and Insula Hypothesis” – the theory that these brain regions are stuck in a hyper-alert state, triggering physical symptoms
Neuroplasticity exercises – including “The Accelerator”, visualisation, language patterns, and movement
Parts Work – recognising and releasing internal conflicts and emotional patterns
Meditation & breathwork – to support calm and regulation
Lifestyle support – modules on boundaries, trauma, pacing, nutrition, and long-term healing mindset
Daily short practices – designed to be repeated throughout the day
It aims to gently rewire the brain's conditioned stress responses that are keeping the body in survival mode.
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Strong, supportive online community and frequent live sessions
Based on 20+ years of clinical and personal experience; includes clinical research trial evidence showing positive results for Long COVID and ME/CFS
Some people find it gentle and effective, while others may prefer different pacing or a less structured approach
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"Ashok’s warmth and explanations gave me hope from day one." They felt the daily practice built a sense of safety and control.
One participant said: "This programme has given me my life back – I’m travelling and socialising again without crashes." They valued the structure and repetition.
A practitioner who had CFS for years wrote a long, sceptic-turned-advocate reflection (https://theneuropath.com/chronic-fatigue-syndrome/my-experience-with-the-gupta-retraining-program-for-chronic-fatigue-syndrome/): "Within 2-3 weeks I noticed vast improvements in my energy and ability to work fairly normally." Takeaway - early wins are possible, but consistency matters for consolidation.
The same author later updated readers on life after the programme: "I am much better now... running my clinic and living a fairly normal life." Takeaway - gains can sustain when tools are kept in use during stressful periods.
Users often report mental and emotional calm first, then physical gains.
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Offers a 28-day free trial
One-time cost of £389.00 GBP / $519.78 USD / €448.94 EUR, with a 1-year money-back guarantee (check it out here: Gupta)
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Free 28-day trial available, no credit card required to sign up, providing access to a selection of modules and tools before committing. guptaprogram.com/free-trial
The flexible subscription model and refund policy make it low-risk for those with chronic illness.
Some past users have reported negotiating extended access or payment flexibility when disclosing illness or financial hardship.
Occasional promotions or partner codes may offer small discounts, but these are not regularly advertised.
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